Investigating the Temporal Stability of 3D-Printed PLA Samples under Ambient Storage Conditions

CT Attenuation Stability in 3D Printed Materials

Authors

DOI:

https://doi.org/10.63187/ampas.31

Keywords:

3D Printing, Phantom, Stability, computed tomography

Abstract

Purpose: This study aims to evaluate the longitudinal radiological stability of 3D-printed PLA-based materials under ambient storage conditions, with varying infill densities and flow rates, in order to understand the impact of these factors on their use in medical imaging and radiation therapy.

Methodology: Twenty-five cylindrical samples were 3D printed using three PLA-based filaments (Lightweight PLA, Premium PLA, and StoneFil), with varying infill densities and flow rates. The samples were stored in ambient room conditions, and their radiological properties were measured over a 6-month period using CT scans. Hounsfield Unit (HU) values were analyzed using a leave-one-out approach and linear regression analysis to assess temporal stability and the relationship between printing parameters and HU values.

Findings: The results demonstrated minimal variations in HU values, with most measurements falling within the limits of agreement, indicating stable radiological properties across all filament types. A strong linear correlation was observed between printing parameters and HU values (R² > 0.99).

Conclusion: The study confirms the stability of 3D-printed PLA-based materials in typical environmental conditions over a 6-month period. These findings support the use of 3D-printed phantoms in medical applications, although further research is needed to explore the effects of UV exposure, higher levels of humidity, and other environmental factors on long-term material stability.

References

Tino R, Yeo A, Leary M, Brandt M, Kron T. A systematic review on 3D-Printed imaging and dosimetry phantoms in radiation therapy. Technol Cancer Res Treat 2019;18:1–14. https://doi.org/10.1177/1533033819870208.

Filippou V, Tsoumpas C. Recent advances on the development of phantoms using 3D printing for imaging with CT, MRI, PET, SPECT, and ultrasound. Med Phys 2018;45:e740–60. https://doi.org/10.1002/mp.13058.

Jreije A, Mutyala SK, Urbonavičius BG, Šablinskaitė A, Keršienė N, Puišo J, et al. Modification of 3D Printable Polymer Filaments for Radiation Shielding Applications. Polymers (Basel) 2023;15. https://doi.org/10.3390/polym15071700.

Ceh J, Youd T, Mastrovich Z, Peterson C, Khan S, Sasser TA, et al. Bismuth infusion of ABS enables additive manufacturing of complex radiological phantoms and shielding equipment. Sensors (Switzerland) 2017;17:1–11. https://doi.org/10.3390/s17030459.

Lee MY, Han B, Jenkins C, Xing L, Suh TS. A depth-sensing technique on 3D-printed compensator for total body irradiation patient measurement and treatment planning. Med Phys 2016;43:6137–44. https://doi.org/10.1118/1.4964452.

Zhao Y, Moran K, Yewondwossen M, Allan J, Clarke S, Rajaraman M, et al. Clinical applications of 3-dimensional printing in radiation therapy. Medical Dosimetry 2017;42:150–5. https://doi.org/10.1016/j.meddos.2017.03.001.

Nikiema D, Balland P, Sergent A. Study of the Mechanical Properties of 3D-printed Onyx Parts: Investigation on Printing Parameters and Effect of Humidity. Chinese Journal of Mechanical Engineering: Additive Manufacturing Frontiers 2023;2:100075. https://doi.org/10.1016/j.cjmeam.2023.100075.

Faust JL, Kelly PG, Jones BD, Roy-Mayhew JD. Effects of coefficient of thermal expansion and moisture absorption on the dimensional accuracy of carbon-reinforced 3D printed parts. Polymers (Basel) 2021;13. https://doi.org/10.3390/polym13213637.

Banjo AD, Agrawal V, Auad ML, Celestine ADN. Moisture-induced changes in the mechanical behavior of 3D printed polymers. Composites Part C: Open Access 2022;7. https://doi.org/10.1016/j.jcomc.2022.100243.

Demirtaş MS, Avcıoğlu E. Ambient relative humidity effects on mechanical properties of FDM 3D printed PLA components. Phys Scr 2023;98. https://doi.org/10.1088/1402-4896/accfcf.

Brunner J, Langgartner L, Danhel H, Birkfellner W, Richter C, Wagenaar D, et al. Dosimetric characteristics of 3D-printed and epoxy-based materials for particle therapy phantoms. Front Phys 2024;12. https://doi.org/10.3389/fphy.2024.1323788.

Ozsoykal I, Yurt A. Introduction of a Novel Technique in Density-Adjusted 3D Printing for the Manufacture of Soft-Tissue-Equivalent Radiological Phantoms. Applied Sciences (Switzerland) 2024;14. https://doi.org/10.3390/app14020509.

Downloads

Published

2025-05-27

How to Cite

Özsoykal, İsmail, Yurt, A., & Selver, M. A. (2025). Investigating the Temporal Stability of 3D-Printed PLA Samples under Ambient Storage Conditions: CT Attenuation Stability in 3D Printed Materials. Advances in Medical Pyhsics and Applied Sciences, 1(2), 45–52. https://doi.org/10.63187/ampas.31